Gin and other Drugs

Isoniazid and other drugs.

The known efficacy of modern drugs with prolonged treatment in leprosy limits the opportunity for experiment with new drugs which also require consid�rable time to give a true indication of their usefulness. Experiments are generally limited to a few in­ dividual cases. Unfortunately, in a disease of remission and re­ lapses, a true picture cannot be obtained from a few cases. This report does ...

Cognitive Functions in Epileptic Patients on Lamotrigine and Other Antiepileptic Drugs

Background and purpose: Anti-epileptic drugs (AEDs) can affect cognitive functions. The purpose of this study was to investigate the effects of lamotrigine (LT) on cognitive functions of patients with epilepsy. Materials and methods: A study with retrospective cohort design was carried out in which we assessed cognitive functions of 20 IGE patients attending Sari Bu Ali Hospital, and 12 health...

Adrenoceptor - Activating & Other Sympathomimetic Drugs

The ultimate effects of sympathetic stimulation are mediated by release from nerve terminals of norepinephrine that serves to activate the adrenoceptors on postsynaptic sites. Also, in response to a variety of stimuli such as stress, the adrenal medulla releases epinephrine, which is transported in the blood to target tissues; in other words, epinephrine acts as a hormone. Drugs that mimic the ...

Interactions between antihypertensive agents and other drugs.

N-Glucuronidation of Drugs and Other Xenobiotics

UDP-glucuronosyltransferases (UGTs) are a family of metabolic enzymes responsible for the detoxification of a wide range of endoand xenobiotics, including drugs. UGTmediated metabolism is a major determinant of the pharmacokinetic behavior of many drugs in the human body, contributing to parameters such as bioavailability and elimination. UGTs catalyze the transfer of glucuronic acid from UDP-g...